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Updated: Jan 16, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Current Topics in OCT Applications in Vitreoretinal Surgery
Shintaro Horie1, Takeshi Yoshida2, Kyoko Ohno-Matsui1
1Department of Ophthalmology and Visual Science, Institute of Science Tokyo, Tokyo 113-8519, Japan.
Abstract:
Optical coherence tomography (OCT) is an indispensable tool in modern ophthalmology, where it is used in prior examinations, among various instruments, to assess macular or vitreoretinal diseases. Pathological macular/retinal conditions are almost always examined and evaluated with OCT before and after treatment. Vitreoretinal surgery is one of the most effective treatment options for vitreoretinal diseases. OCT data collected during the treatment of these diseases has accumulated, leading to the reporting of a variety of novel biomarkers and valuable findings related to OCT usage. Recent substantial developments in technology have brought ultra-high-resolution spectral domain/swept source OCT, ultra-widefield OCT, and OCT angiography into the retinal clinic. Here, we review the basic development of the instrument and general applications of OCT in ophthalmology. Subsequently, we provide up-to-date OCT topics based on observations in vitreoretinal surgery.
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