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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization
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Interferon Regulator Factor 5: A Novel Inflammatory Marker and Promising Therapeutic Target in Ulcerative Colitis

Karima Farrag1, Aysegül Aksan2, Marina Korotkova3,4

  • 1Medical Clinic 1, University Hospital, Goethe University Frankfurt, 60594 Frankfurt am Main, Germany.

Biomedicines
|September 27, 2025
PubMed
Summary

Interferon regulatory factor 5 (IRF5) is elevated in ulcerative colitis (UC) patients, correlating with disease activity. This finding suggests IRF5 may serve as a biomarker for inflammatory bowel disease (IBD) therapeutic interventions.

Keywords:
IRF5immunohistochemistryinflammatory bowel diseaseulcerative colitis

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