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Published on: February 7, 2018
Nutraceuticals Against Oxidative Stress in Allergic Diseases
Marilena Di Salvo1, Alessandra Ventre1, Enrica Dato1
1Department of Clinical and Experimental Medicine, Unit and School of Allergy and Clinical Immunology, University Hospital of Messina, University of Messina, 98125 Messina, Italy.
Dietary antioxidants and nutraceuticals can help manage allergic disorders by reducing oxidative stress. While promising results exist for conditions like asthma and eczema, more large-scale studies are needed to confirm efficacy.
Area of Science:
- Dietary antioxidants and nutraceuticals
- Allergic disorders
- Oxidative stress
Background:
- Antioxidant mechanisms involve endogenous and exogenous compounds crucial for counteracting oxidative stress.
- Phytochemicals from fruits and vegetables possess beneficial properties for health and disease prevention.
- Nutraceuticals are bioactive food components with positive health effects, potentially preventing or treating disorders.
Purpose of the Study:
- To review the applications of nutraceuticals in managing allergic disorders.
- To explore the role of exogenous dietary antioxidant supplementation in conditions like asthma, dermatitis, and food allergies.
Main Methods:
- Literature review of studies on exogenous dietary antioxidant supplementation in allergic conditions.
- Analysis of research investigating the impact on oxidative stress markers and antioxidant systems.
Main Results:
- Promising results observed in conditions such as bronchial asthma, atopic dermatitis, and food allergies.
- Positive outcomes linked to reduced oxidative stress markers and enhanced antioxidant systems.
- Anti-inflammatory effects were noted in some cases.
Conclusions:
- Scientifically standardized exogenous nutraceuticals show effectiveness in managing allergic disorders.
- Further large-scale, unbiased studies are required, especially those incorporating a wider array of oxidative stress biomarkers.
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