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Automated Brain Tumor MRI Segmentation Using ARU-Net with Residual-Attention Modules
Erdal Özbay1, Feyza Altunbey Özbay2
1Department of Computer Engineering, Firat University, 23119 Elazig, Türkiye.
Diagnostics (Basel, Switzerland)
|September 27, 2025
Summary
This study introduces Attention Res-UNet (ARU-Net), a novel deep learning model for accurate brain tumor segmentation in MRI scans. ARU-Net significantly improves segmentation accuracy and generalization, offering a reliable tool for clinical applications.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computational Biology
Background:
- Accurate brain tumor segmentation in MRI is crucial for diagnosis and treatment planning.
- Existing methods struggle with the heterogeneity and complexity of tumor regions.
Purpose of the Study:
- To develop a robust, automated deep learning method for precise brain tumor segmentation.
- To enhance segmentation accuracy and generalization capabilities.
Main Methods:
- Proposed Attention Res-UNet (ARU-Net) architecture integrating residual connections, Adaptive Channel Attention (ACA), and Dimensional-space Triplet Attention (DTA).
- Pre-processed MRI images using CLAHE, denoising, and Linear Kuwahara filtering.
- Trained ARU-Net on the BTMRII dataset and compared against baseline U-Net, DenseNet121, and Xception models.
Main Results:
- ARU-Net achieved 98.3% accuracy, 98.1% DSC, 96.3% IoU, and a superior F1-score.
- Demonstrated significant improvements over baseline U-Net, particularly in segmenting heterogeneous tumor structures.
- Visualizations confirmed smoother boundaries and more precise tumor contours across all tumor classes.
Conclusions:
- ARU-Net offers a highly reliable and precise solution for automated brain tumor segmentation.
- The model's superior performance highlights its potential for clinical application.
- Contributes novel insights to medical image analysis and deep learning in healthcare.

