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Related Experiment Videos

Premotor cortical ablations in monkeys: contralateral changes in visually guided reaching behavior.

L Moll, H G Kuypers

    Science (New York, N.Y.)
    |October 21, 1977
    PubMed
    Summary

    Brain damage in rhesus monkeys disrupts arm reaching, causing them to move straight towards food instead of around obstacles. This suggests disinhibition of brainstem pathways controlling arm movements.

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    Area of Science:

    • Neuroscience
    • Primate motor control
    • Cognitive neuroscience

    Background:

    • The premotor and supplementary motor areas are crucial for planning and executing complex movements, including reaching.
    • Understanding how these areas interact with subcortical pathways is essential for deciphering motor control.

    Purpose of the Study:

    • To investigate the role of premotor and supplementary motor areas in visually guided reaching around obstacles.
    • To determine the effects of ablating these areas on reaching behavior in rhesus monkeys.

    Main Methods:

    • Surgical ablation of the premotor and supplementary motor areas in rhesus monkeys.
    • Behavioral testing involving reaching for food rewards around transparent obstacles.
    • Analysis of reaching trajectories and movement patterns.

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    Main Results:

    • Ablation impaired the ability to reach around transparent obstacles.
    • Monkeys exhibited a tendency to reach directly towards the visible food reward.
    • This suggests a reliance on simpler, visually-guided reaching strategies post-lesion.

    Conclusions:

    • The premotor and supplementary motor areas are critical for complex, obstacle-avoiding reaching.
    • Damage to these areas may lead to disinhibition of brainstem pathways, resulting in straight-line reaching.
    • This highlights the hierarchical organization of motor control in primates.