Innovations in Intraocular Lens Power Calculation-A Review
Wiktor Stopyra1,2, Andrzej Grzybowski3,4
1MW-Med Eye Centre, 31-416 Krakow, Poland.
Journal of Clinical Medicine
|September 27, 2025
Summary
Accurate intraocular lens (IOL) power calculation is crucial for phacoemulsification. This review analyzes new AI-based and vergence formulas, highlighting advancements in IOL power selection and accuracy assessment.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Medical Technology
Background:
- Accurate intraocular lens (IOL) power calculation is critical for successful phacoemulsification outcomes.
- The development of novel IOL power calculation formulas is an ongoing area of research in ophthalmology.
Purpose of the Study:
- To review and analyze the latest intraocular lens (IOL) power calculation formulas published between 2019 and 2025.
- To classify new formulas and assess their accuracy in predicting refractive outcomes after cataract surgery.
Main Methods:
- A narrative review of peer-reviewed studies published from 2019-2025, identified through extensive database searches.
- Inclusion of 33 studies meeting PRISMA methodology criteria, focusing on phacoemulsification and IOL power calculation.
- Analysis of ten recently introduced formulas, including AI-based, vergence, and ray-tracing methods.
Main Results:
- Ten new IOL power calculation formulas were identified: five AI-based, four vergence, and one ray-tracing.
- Artificial intelligence is a dominant trend in the development of new IOL power calculation formulas.
- Various methods for assessing formula accuracy were discussed, with root mean square absolute error noted.
Conclusions:
- The field of IOL power calculation is rapidly evolving with the introduction of new formulas.
- Artificial intelligence plays a significant role in the advancement of IOL power calculation technology.
- Continuous development of methods to accurately assess the performance of IOL power calculation formulas is essential.
Keywords:
artificial intelligenceintraocular lens power calculation formulasphacoemulsificationroot mean square absolute errorMore Related Videos
Related Concept Videos
Focusing of Light in the Eye
5.4K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.4K
Angle Closure Glaucoma: Treatment
1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
Open Angle Glaucoma: Treatment
963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
963
Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K


