Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary
Ricardo Miguel Luque Bernal1, Angy Carolina Villamil Duarte1, Ernesto Fajardo Chavarro2
1Anatomy Unit, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá 111221, Colombia.
Insights
This study on aortic aneurysms and dissections in Colombia found infrarenal abdominal aortic aneurysms were most common. Larger aortic diameter predicted mortality in aneurysm cases, but not in dissections.
Area of Science:
- Vascular Surgery
- Radiology
- Epidemiology
Background:
- Aortic aneurysms and dissections are critical vascular conditions with significant mortality.
- Accurate characterization of anatomical and clinical features is vital for improving diagnosis and treatment.
- Colombian patient data is crucial for understanding regional variations in these diseases.
Purpose of the Study:
- To detail the demographic, clinical, and imaging-based anatomical characteristics of aortic aneurysms and dissections.
- To analyze predictors of in-hospital mortality in this Colombian cohort.
- To provide region-specific data for Latin American clinical decision-making.
Main Methods:
- Retrospective, descriptive, observational study of 539 adult patients.
- Inclusion criteria: radiologically confirmed aortic aneurysm or dissection via CTA (2010-2021).
- Data extracted: demographic, clinical, morphological. Statistical analysis: chi-squared, Mann-Whitney U, logistic regression.
Main Results:
- Infrarenal abdominal aortic aneurysms were most frequent (63.7%); 92% were fusiform.
- Saccular aneurysms were more common in females and non-infrarenal segments.
- Aortic diameter independently predicted mortality in aneurysm patients (OR=1.03), but no significant predictors were found for dissection mortality.
Conclusions:
- Infrarenal location and fusiform shape are predominant in this Colombian cohort.
- Morphological patterns correlate with sex and anatomical distribution.
- While trends exist, specific mortality predictors for aortic dissections remain elusive in this population, emphasizing the need for tailored, region-specific management.
Abstract:
Background and Objectives: Aortic aneurysms and dissections are life-threatening vascular disorders with high morbidity and mortality. Enhancing diagnostic and therapeutic strategies requires a precise characterization of their anatomical and clinical features. This study aimed to detail the demographic, clinical, and imaging-based anatomical characteristics of aortic aneurysms and dissections in a cohort of Colombian patients. Materials and Methods: We conducted a retrospective, descriptive, observational study at a tertiary hospital in Bogotá, Colombia. Adult patients (≥18 years) with radiologically confirmed aortic aneurysm or dissection on computed tomography angiography (CTA) between 2010 and 2021 were included. Demographic, clinical, and morphological data were extracted. Associations were explored using chi-squared and Mann-Whitney U tests. Multivariate logistic regression was applied to identify independent predictors of in-hospital mortality. Results: This study included 539 patients (mean age: 69.3 ± 11.5 years; 53.6% male). Infrarenal abdominal aortic aneurysms were the most frequent (63.7%), with fusiform morphology observed in 92% of cases. Saccular aneurysms were significantly more common in females (p = 0.0267) and in non-infrarenal segments (p = 0.0162). Among patients with aneurysms, aortic diameter was an independent predictor of mortality (OR = 1.03; 95% CI: 1.01-1.05; p < 0.001). No individual variable significantly predicted mortality in dissection cases. Conclusions: In this cohort, infrarenal location and fusiform shape predominate. Morphological patterns were associated with sex and anatomical distribution. Although trends were observed, no statistically significant predictors of death were identified in dissection cases. These findings highlight the value of early detection and tailored management and reinforce the importance of generating region-specific data to inform clinical decision making in Latin American settings.
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