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Can Sirtuin 1 Serve as a Therapeutic Target in Pulmonary Arterial Hypertension? A Comprehensive Review

Sandra Budziak1, Monika Kloza1, Anna Krzyżewska1

  • 1Department of Experimental Physiology and Pathophysiology, Medical University of Białystok, 15-222 Białystok, Poland.

Molecules (Basel, Switzerland)
|September 27, 2025
PubMed
Abstract

Keywords:
inflammationmitochondrial biogenesisoxidative stressproliferationpulmonary arterial hypertensionpulmonary artery endothelial cellspulmonary artery vascular smooth muscle cellspulmonary hypertensionsirtuin 1vascular remodeling

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