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A Simple Deterministic Model of Protection and Cost Benefits from Vaccinating Indian Cattle Against Infectious Bovine
Bhaskar Ganguly1, Sarvesh Tayshete1, Priyabrata Pattnaik1
1Indian Immunologicals Limited, Rakshapuram, Hyderabad 500032, India.
Pathogens (Basel, Switzerland)
|September 27, 2025
Summary
An indigenously developed vaccine offers a new strategy for controlling Infectious Bovine Rhinotracheitis (IBR) in India. Optimal control involves primary vaccination, bi-annual boosters, and farm biosecurity for 70% cattle coverage.
Area of Science:
- Veterinary Medicine
- Epidemiology
- Economic Entomology
Background:
- Infectious Bovine Rhinotracheitis (IBR) is a significant endemic disease in India, causing substantial economic losses in the dairy sector.
- Limited access to affordable, indigenously manufactured vaccines previously hindered widespread control efforts.
- Existing IBR control strategies from other countries may not be directly transferable to India's unique farming systems and social contexts.
Purpose of the Study:
- To develop an optimal immunization strategy for controlling Infectious Bovine Rhinotracheitis (IBR) in India.
- To evaluate the benefits and costs associated with vaccination against IBR.
- To propose evidence-based recommendations for vaccination programs tailored to Indian dairy enterprises.
Main Methods:
- Linear deterministic modeling was utilized to simulate and analyze vaccination strategies.
- The study assessed both animal protection and economic factors related to IBR control.
- Model parameters were adjusted to reflect India's specific agricultural and social conditions.
Main Results:
- Effective IBR control requires a combination of robust vaccination practices, stringent farm biosecurity, and regular re-vaccination.
- A recommended strategy includes primary vaccination with two doses, followed by biannual single-dose boosters.
- Achieving 70% vaccination coverage in the cattle population is crucial for successful disease control.
Conclusions:
- The newly available indigenously manufactured inactivated DIVA vaccine presents a viable tool for IBR management in India.
- A comprehensive approach integrating vaccination, biosecurity, and strategic re-vaccination is essential for controlling IBR.
- The proposed vaccination program provides a cost-effective and protective strategy for the Indian dairy industry.
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