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Millifluidics for Chemical Synthesis and Time-resolved Mechanistic Studies
Published on: November 27, 2013
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A Novel Double-Diamond Microreactor Design for Enhanced Mixing and Nanomaterial Synthesis
Qian Peng1, Guangzu Wang2, Chao Sheng2
1CAS Key Laboratory of Mechanical Behavior and Design of Materials, School of Engineering Science, University of Science and Technology of China, Hefei 230026, China.
Micromachines
|September 27, 2025
Summary
The novel Double-Diamond Reactor (DDR) enhances mixing and nanoparticle synthesis. This microreactor design minimizes clogging and pressure drops for efficient chemical processes.
Area of Science:
- Chemical Engineering
- Materials Science
- Fluid Dynamics
Background:
- Conventional microreactors face challenges with mass transfer, flow resistance, and clogging.
- Hydrodynamic principles can be leveraged to improve mixing efficiency in microfluidic devices.
Purpose of the Study:
- Introduce a novel planar passive microreactor, the Double-Diamond Reactor (DDR).
- Address limitations of conventional microreactors, including inefficient mass transfer and clogging.
- Enhance mixing and control nanoparticle synthesis through optimized hydrodynamic principles.
Main Methods:
- Utilized splitting-turning-impinging (STI) hydrodynamic principles.
- Employed Computational Fluid Dynamics (CFD) for guided optimization.
- Conducted experimental evaluations using Villermaux-Dushman tests and BaSO4 nanoparticle synthesis.
Main Results:
- Achieved near-perfect mixing with a segregation index (Xs) as low as 0.027.
- Synthesized BaSO4 nanoparticles with a 46% smaller average size (95 nm) and narrower distribution (σg=1.27).
- Maintained low pressure drops (<20 kPa at 60 mL·min⁻¹).
Conclusions:
- The DDR design effectively enhances mixing via chaotic advection and eliminates stagnant zones.
- Demonstrated superior performance in high-throughput nanomaterial synthesis with precise particle control.
- Offers a scalable and energy-efficient solution for advanced chemical processes and microreactor technology.

