Related Experiment Video
Updated: Jan 16, 2026
11:49
Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
Published on: March 9, 2015
16.6K
Trace Elements in Post-Mortem Tissues: A Review of Current Evidence and Forensic Challenges
Claudia Trignano1,2, Angela Sabalic1,2,3, Andrea Pisano1,2
1Department of Biomedical Science, University of Sassari, 07100 Sassari, Italy.
Toxics
|September 27, 2025
Summary
Forensic analysis of trace elements and heavy metals in post-mortem tissues offers valuable insights. However, the lack of standardized guidelines and reference values hinders reliable interpretation in investigations.
Area of Science:
- Forensic Science
- Toxicology
- Analytical Chemistry
Background:
- Trace elements and heavy metals are crucial for forensic investigations, aiding in individual identification, lifestyle reconstruction, and linking criminal activities.
- Current forensic applications are limited by a lack of standardized guidelines and established post-mortem reference values.
Purpose of the Study:
- To review the forensic potential of trace element and heavy metal analysis in post-mortem tissues.
- To identify limitations and the need for standardization in the field.
Main Methods:
- A comprehensive literature review was conducted over the past ten years.
- The review adhered to the PRISMA statement, analyzing studies on post-mortem trace element and heavy metal analysis.
Main Results:
- Out of 247 records, 19 articles were included, highlighting methodological heterogeneity.
- Preliminary reference values for cadmium (Cd) and mercury (Hg) exist, but validated post-mortem ranges are scarce.
- The need for standardized guidelines and reference values was consistently identified.
Conclusions:
- Trace element and heavy metal analysis, including elements like Cd, Hg, Pb, Mn, Al, Cu, Zn, Fe, Tl, and 210Po, shows significant forensic potential.
- Standardized protocols and validated post-mortem reference values are urgently required to enhance the interpretability and reliability of forensic findings.
