Related Experiment Video
Updated: May 5, 2026
Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
Advances in Second Near-Infrared Window Photothermal Agents and Photothermal Therapy for Tumors in Interdisciplinary
Runxuan Zhou1, Yufei Chen2, Shuxi Yao1
1Cancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China.
Abstract:
Cancer continues to pose a significant threat to human health. While early diagnosis has improved survival rates for many cancer patients, a substantial number still do not achieve the desired treatment outcomes. Therefore, it is imperative to develop novel therapeutic approaches for tumor management. Second near-infrared window photothermal therapy has garnered considerable attention from researchers due to its effective tumor-killing capabilities and minimal side effects. This review commences by summarizing the advancements in second near-infrared photothermal agents, alongside an evaluation of the advantages and disadvantages of various photothermal agents. Subsequently, we highlight the benefits of combining photothermal therapy with other treatment modalities. Finally, we present a compilation of reports detailing the application of photothermal therapy in the treatment of various tumor types in clinical settings. In the conclusion, we underscore the challenges and potential research directions associated with photothermal therapy. Our article aims to facilitate interdisciplinary research in the fields of nanomedicine and clinical medicine.
Insights
Second near-infrared window photothermal therapy offers effective tumor destruction with few side effects. This review explores advancements in photothermal agents and their combination with other treatments for improved cancer therapy.
Area of Science:
- Oncology
- Nanomedicine
- Biomedical Engineering
Background:
- Cancer remains a major global health challenge, necessitating innovative treatment strategies beyond early diagnosis.
- While advancements exist, many patients still require more effective tumor management solutions.
- Second near-infrared (NIR) window photothermal therapy (PTT) shows promise for potent tumor eradication with minimal adverse effects.
Purpose of the Study:
- To review the latest developments in second NIR window photothermal agents.
- To evaluate the pros and cons of different photothermal agents.
- To explore the synergistic potential of combining PTT with other therapeutic modalities.
Main Methods:
- Comprehensive literature review of second NIR window photothermal agents.
- Analysis of existing data on PTT efficacy and safety profiles.
- Compilation of clinical case studies and research reports on PTT applications.
Main Results:
- Summary of recent progress in second NIR PTT agents.
- Comparative assessment of various photothermal agents, detailing their strengths and limitations.
- Evidence supporting the enhanced efficacy of combination therapies involving PTT.
Conclusions:
- PTT is a promising therapeutic modality for diverse cancer types.
- Combining PTT with other treatments can improve patient outcomes.
- Further research is needed to address challenges and optimize PTT for clinical application, fostering interdisciplinary collaboration.
More Related Videos
Related Concept Videos
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
There are several types of targeted therapies against...