MoveLab^®: Validation and Development of Novel Cross-Platform Gait and Mobility Assessments Using Gold Standard Motion...

Wearable health assessment devices enable real-time clinical- and home-based patient monitoring. Human gait analysis is a widely accepted musculoskeletal assessment. The 30 s Sit-to-Stand (STS) and Timed-Up-and-Go (TUG) are clinical frailty assessments used alongside gait analysis. This study assessed the reliability and validity of the MoveLab^® (Agile Kinetic 2024) approach to measure gait spatiotemporal parameters (STPs), STS, and TUG using a waist-worn mobile phone, compared to the Gold Standard 3D marker-based motion capture (Qualisys AB, Sweden) and the Clinical Standard assessment of the STS and TUG test methods. Movement data, recorded simultaneously for 25 healthy volunteers (14 female and 11 male, Age = 31.8 ± 11.6 yrs) in a Biomechanics Laboratory using the Gold Standard system, the Clinical Standard assessments, and MoveLab^®, was analyzed using Intraclass Correlation (ICC) and Bland-Altman plots (Python) to quantify the correlations, consistency, and significance across the output parameters. Comparing the methods, the STP consistency ranged from acceptable to good for all the tested parameters (ICC 0.299-0.894). The highest and lowest correlations were cycle time and terminal double support time, respectively. The TUG showed good agreement (ICC 0.757). Generally, an equal number of MoveLab^® STS repetitions were observed. MoveLab^® demonstrated validity and reliability for a range of key movement parameters using a pouch-worn mobile phone device in healthy adults in a controlled laboratory environment.