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Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
Published on: December 20, 2024
Recurrent pneumococcal OPSI after splenectomy: The need for optimized vaccination and prophylaxis
Masashi Nishiyama1, Kyoko Yokota2, Akihito Matsuoka3
1Department of General Internal Medicine, Mitoyo General Hospital, Kan'onji, Japan.
Patients who have undergone splenectomy face a high risk of overwhelming post-splenectomy infection (OPSI). This case highlights the need for improved vaccines and prophylaxis to prevent recurrent OPSI from encapsulated bacteria like Streptococcus pneumoniae.
Area of Science:
- Infectious Diseases
- Immunology
- Vaccinology
Background:
- Splenectomy increases the risk of severe sepsis from encapsulated bacteria, particularly Streptococcus pneumoniae.
- Overwhelming post-splenectomy infection (OPSI) is a life-threatening condition requiring preventative strategies.
- Standard vaccinations may not cover all relevant serotypes causing OPSI.
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