Related Experiment Video
Updated: Jan 16, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Fatal Pneumocephalus Caused by Hypervirulent Klebsiella pneumoniae, Germany
Abstract:
We report a fatal case of pneumocephalus in Germany caused by hypervirulent Klebsiella pneumoniae sequence type 23, confirmed by using clinical, histopathologic, and genomic analyses. The patient reported no travel history, suggesting local emergence. This unusual case reveals an unclear pathogen prevalence and demonstrates the need for increased awareness of global spread.
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09:17A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
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