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Updated: Jan 16, 2026

Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System
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Author Spotlight: Advancing Antibiotic Resistance Research Using an Efflux-Deficient Bacterial Strain and a Single-Copy Gene Expression System

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EefR mutations drive sanguinarine resistance by activating cryptic multidrug efflux pumps in AcrB-Null Escherichia

Hao-Jie Shen1, Jun-Feng Wang1, Zheng-Jie Xue1

  • 1College of Life Sciences, Zhejiang Chinese Medical University, Hangzhou, China.

Virulence
|September 29, 2025
PubMed

Keywords:
Escherichia coliTetR family regulatorefflux pumpmultidrug resistanceresistance-nodulation-cell division (RND) pumpsanguinarine

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