Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

14.1K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
14.1K
Improving Translational Accuracy02:07

Improving Translational Accuracy

3.5K
3.5K
Woodward–Hoffmann Selection Rules and Microscopic Reversibility01:34

Woodward–Hoffmann Selection Rules and Microscopic Reversibility

3.8K
Electrocyclic reactions, cycloadditions, and sigmatropic rearrangements are concerted pericyclic reactions that proceed via a cyclic transition state. These reactions are stereospecific and regioselective. The stereochemistry of the products depends on the symmetry characteristics of the interacting orbitals and the reaction conditions. Accordingly, pericyclic reactions are classified as either symmetry-allowed or symmetry-forbidden. Woodward and Hoffmann presented the selection criteria for...
3.8K
Structural Classification of Joints01:20

Structural Classification of Joints

7.0K
Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
A fibrous joint is where the adjacent bones are united by fibrous connective...
7.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stellar feedback drives the baryon deficiency in low-mass galaxies.

Science advances·2026
Same author

Construction of a public health emergency information system framework: A case study of Zhuhai city, China.

PloS one·2026
Same author

Federated target trial emulation for time-to-event outcomes via POLARIS: Pooled-equivalent One-shot Likelihood Aggregation for Real-world Inference in Survival.

Research square·2026
Same author

Virulence Phenotypes Differentiate Persistent vs. Resolving Isolates of Human <i>Staphylococcus aureus</i> Bacteremia.

Antibiotics (Basel, Switzerland)·2026
Same author

Epigenomic reprograming underlies internodal developmental heterogeneity in rapidly elongating bamboo shoots.

Plant physiology·2026
Same author

Dual-mode biosensing system based on stimuli-responsive DNA hydrogel and polyadenine-AuNPs for sensitive and rapid detection of Escherichia coli O157:H7.

Food chemistry·2026

Related Experiment Video

Updated: Jan 16, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

1.0K

A Statistical Framework of Watermarks for Large Language Models: Pivot, Detection Efficiency and Optimal Rules.

Xiang Li1, Feng Ruan2, Huiyuan Wang1

  • 1University of Pennsylvania.

Annals of Statistics
|September 29, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a new framework for creating and detecting watermarks in large language model (LLM) text. The framework optimizes watermark detection, improving accuracy in identifying AI-generated content.

Related Experiment Videos

Last Updated: Jan 16, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

1.0K

Area of Science:

  • Computer Science
  • Artificial Intelligence
  • Natural Language Processing

Background:

  • Large language models (LLMs) like ChatGPT generate text that requires methods for distinguishing it from human writing.
  • Watermarking, embedding statistical signals into LLM text, is a key technique for detecting AI-generated content.

Purpose of the Study:

  • To introduce a general and flexible framework for evaluating watermark statistical efficiency.
  • To design powerful detection rules for LLM-generated text watermarks.

Main Methods:

  • The framework utilizes hypothesis testing for watermark detection.
  • It involves selecting a pivotal statistic and a secret key to control false positive rates.
  • Closed-form expressions for asymptotic false negative rates are derived to evaluate detection rule power.

Main Results:

  • The framework reduces optimal detection rule determination to a minimax optimization problem.
  • Applied to two representative watermarks, the framework yielded significant findings for watermark implementation.
  • Theoretically derived optimal detection rules demonstrated competitive or superior performance compared to existing methods in numerical experiments.

Conclusions:

  • The developed framework provides a principled approach to designing and analyzing LLM text watermarks.
  • Optimal detection rules derived from this framework offer improved accuracy in distinguishing AI-generated text.