Friedreich Ataxia and Related Diabetes: Therapeutic Approach Targeting Mitochondrial Dysfunction.
Pichakacheri Sureshkumar1,2,3, Sidharth S Kumar1, Johny Cheriyan4
1Dr. Suresh's Diabcare India Diabetes Center, Calicut, Kerala 673017, India.
JCEM Case Reports
|September 29, 2025
Summary
Mitochondriotropic agents may improve glycemic control and neurological symptoms in patients with Friedreich
Area of Science:
- Neurology
- Endocrinology
- Mitochondrial Medicine
Background:
- Friedreich ataxia (FA) is a rare inherited neurodegenerative disorder.
- FA patients often develop diabetes mellitus (DM), complicating management.
- Mitochondrial dysfunction is implicated in both FA pathogenesis and insulin resistance.
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