Related Experiment Video
Updated: Jan 16, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Eosinophilic Pleural Effusion as an Unusual Initial Manifestation of IgG4-Related Disease: A Diagnostic Challenge
Parinya Ruenwilai1, Sarawut Kongkarnka2, Athitarn Tangtermpong3
1Division of Pulmonary, Critical Care and Allergy, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, THA.
Abstract:
We report the case of a 79-year-old male who presented with progressive dyspnea over the course of one month. Chest radiography revealed a left-sided pleural effusion. Pleural fluid analysis demonstrated an exudative profile with eosinophil-predominant cytology. Medical thoracoscopy identified multiple hyperpigmented spots on the anterior parietal pleura. Histopathological examination of pleural biopsy specimens confirmed the diagnosis of IgG4-related disease (IgG4-RD). The pleural effusion resolved completely following corticosteroid therapy.
Related Concept Videos
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pericarditis II: Clinical Features and Diagnostic Tests
Pleural Disorders: Types and Brief Description
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

