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Investigating Outcomes Following Distal Upper Extremity Fractures in Chronic Kidney Disease Patients
Daniel Villarreal Acha1, Zuhair Zaidi1, Muhammad H Harirah2
1From the University of Texas Southwestern Medical School, Dallas, TX.
Plastic and Reconstructive Surgery. Global Open
|September 29, 2025
Summary
Chronic kidney disease (CKD) significantly delays distal upper extremity fracture healing and increases complications. Early identification of CKD risks is crucial for optimizing patient care and surgical outcomes.
Area of Science:
- Orthopedic Surgery
- Nephrology
- Bone Metabolism
Background:
- Chronic kidney disease (CKD) impacts bone health and fracture healing.
- Research on distal upper extremity fractures in CKD patients is limited.
- Understanding CKD's effect on fracture outcomes is vital for surgical management.
Purpose of the Study:
- To evaluate the impact of CKD on distal upper extremity fracture healing.
- To identify complications and mortality associated with CKD in these fractures.
- To inform surgical strategies for patients with CKD.
Main Methods:
- Retrospective review of patients with CKD stages 1-4 and end-stage renal disease undergoing distal upper extremity fracture repair.
- Analysis of demographics, CKD stage, comorbidities, surgical details, and complications.
- Radiographic union time assessment and national database validation with propensity-matched controls.
Main Results:
- CKD cohort showed significantly delayed fracture healing (68.4 days) versus controls (50.6 days).
- CKD patients had higher rates of postoperative edema and weakness.
- National database analysis confirmed increased risks for revision surgery in CKD patients.
Conclusions:
- CKD adversely affects outcomes of distal upper extremity fracture repair.
- Tailored perioperative management is essential for CKD patients.
- Early identification of CKD-related risks optimizes patient care and outcomes.
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