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Taking the Translational Science Benefits Model from concept to operationalization: opportunities and challenges in
Jessica Sperling1,2, Eman Ghanem1, Stella Quenstedt1
1Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC, United States.
Frontiers in Public Health
|September 29, 2025
Summary
The Translational Science Benefits Model (TSBM) can be operationalized to measure translational research impact. This paper details how to integrate the TSBM into programs for better data collection and outcome demonstration.
Area of Science:
- Translational Science
- Health Services Research
- Research Impact Assessment
Background:
- The Translational Science Benefits Model (TSBM) was created to conceptualize translational research benefits.
- The TSBM is primarily a conceptual framework, not an operational process.
- There is a need to integrate the TSBM into operational processes to demonstrate research impact.
Purpose of the Study:
- To discuss the integration of the TSBM into operational processes for demonstrating translational research impact.
- To explore TSBM-informed programmatic processes for assessing impact.
- To identify key factors for using the TSBM as a data collection tool.
Main Methods:
- Discussion of three TSBM-informed programmatic processes: case studies, Pilots program reporting, and an organizational database.
- Analysis of key factors for TSBM integration, including 'who' codes data, 'how' outcomes are defined, and 'when' measurement is adapted.
- Consideration of workforce development and translational science-specific outcomes.
Main Results:
- TSBM can be used as a program-integrated operational mechanism.
- Key considerations for TSBM implementation include data coding, outcome definition, and timing.
- Feasibility and validity must be balanced when collecting TSBM data.
Conclusions:
- The TSBM offers valuable lessons for data collection on translational research outcomes.
- Integrating the TSBM can enhance the understanding, demonstration, and augmentation of translational research impact.
- Opportunities exist to expand the TSBM's utility as a data collection tool.
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