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Outcomes In Acute Kidney Injury Requiring Haemodialysis - A Retrospective Cohort Study.
1Belfast City Hospital, 51 Lisburn Road, BT9 7AB.
The Ulster Medical Journal
|September 29, 2025
Summary
Most patients with acute kidney injury requiring intermittent haemodialysis (AKI-IHD) recovered kidney function. Lower 30-day mortality was observed, but heart failure or age over 70 predicted poorer outcomes.
Area of Science:
- Nephrology
- Critical Care Medicine
Background:
- Acute kidney injury requiring intermittent haemodialysis (AKI-IHD) is linked to high morbidity and mortality.
- Limited data exists on AKI-IHD outcomes in Northern Ireland.
Purpose of the Study:
- To explore clinical outcomes in AKI-IHD patients.
- To determine recovery rates of self-sustaining kidney function.
- To investigate 30-day and 2-year mortality predictors.
Main Methods:
- Retrospective review of 188 incident AKI-IHD patients from January 2018-December 2022.
- Data collected from electronic health records.
- Analysis of demographic and clinical outcomes.
Main Results:
- 92% of patients not previously known to nephrology recovered kidney function, versus 59% of those with prior nephrology care.
- Lower baseline creatinine predicted recovery in previously known patients.
- 30-day mortality was 14% (previously unknown) and 9% (previously known).
- Heart failure and age ≥ 70 predicted higher mortality.
- Two-year mortality was similar (35% vs. 37%).
Conclusions:
- The majority of AKI-IHD patients in this cohort recovered kidney function.
- Observed 30-day mortality rates were lower than literature, potentially due to patient selection.
- Heart failure and advanced age are key factors influencing AKI-IHD outcomes.
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