Related Experiment Video
Updated: Jun 27, 2026

Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
Published on: May 20, 2020
Pain relieving effects of Botox injection in the hip joint following a periacetabular osteotomy
Niels Bang1, Bjarne Mygind-Klavsen2, Bent Lund3
1Department of Radiology, Regionshospitalet, Falkevej 1, Silkeborg 8600, Denmark.
Abstract:
Patients with symptomatic hip dysplasia may undergo periacetabular osteotomy (PAO) and 10% of these patients have pain >6 months after the operation. An intra-articular lidocaine injection is used to determine if the pain comes from labral pathology in the hip joint or structures around the hip. To allow the patient a longer period of time to test the hip, we wanted to test if an intra-articular injection of Botox combined with local anaesthetic could reduce pain and allow the patient to test the hip. Eleven patients who received a PAO and suffered from persistent pain at least 6 months postoperative had an intra-articular joint injection with 100IE Botox, 3 ml NaCl water and 3 ml lidocaine. Hip pain on the day of injection and after 6 weeks was evaluated using the Visual Analog Scale score, International Hip Outcome Tool (iHOT-12), and Hip and Groin Outcome Score (HAGOS). Botox in the hip joint reduced the pain level and the iHOT-12 score, with a statistically significant improvement 6 weeks after injection. Hip joint injection of a controlled dosage of 100 IU diluted in 3 ml NaCl solution mixed with lidocaine had no side effects in this study with a limited group of patients. Botox has a promising pain-reducing effect on the hip joint in the majority of patients comparable with findings in knee and shoulder joints. Hip joint injection of a controlled dosage of 100 IU, 3 ml NaCl solution mixed with lidocaine had no side effects in this study with a limited group of patients.
More Related Videos
09:51The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
04:57Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
Published on: April 26, 2024
Related Concept Videos
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Skeletal Muscle Relaxants: Therapeutic Uses