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Updated: Jan 16, 2026

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

Published on: January 13, 2023

COVID-19 Influence on Mandibular Dry Socket Occurrence.

Navid Kazemian¹, Mozhgan Khorami¹, Ricardo Grillo²

¹Student Research Committee, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran.

World Journal of Plastic Surgery

|September 29, 2025

Summary

This summary is machine-generated.

Alveolar osteitis (dry socket) risk increases after mandibular third molar extraction, especially with COVID-19 hospitalization. Females face higher risks, highlighting the need for targeted prevention strategies.

Keywords:

COVID-19 Dry Socket Oral Surgery Osteitis Postoperative Complications Surgery

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Area of Science:

Oral Surgery
Infectious Diseases
Public Health

Background:

Alveolar osteitis (dry socket) is a common complication after tooth extraction, particularly mandibular third molars.
The COVID-19 pandemic's hematologic effects necessitate investigating its impact on dry socket risk.

Purpose of the Study:

To assess the relationship between COVID-19 and dry socket risk in patients undergoing mandibular third molar extraction.
To identify demographic and clinical factors associated with dry socket development post-extraction.

Main Methods:

Retrospective review of patient records from mandibular third molar extractions in 2022.
Data collection included demographics, medical history, smoking, and COVID-19 status (history, hospitalization, vaccination).

Main Results:

Nearly 50% of patients developed dry socket; 94% had a COVID-19 history, and 32.7% were hospitalized for COVID-19.
Females had a significantly higher risk of dry socket compared to males.
No direct link between COVID-19 infection and dry socket was found, but hospitalization showed a correlation.

Conclusions:

Dry socket risk is elevated by corticosteroid use, oral contraceptives, smoking, and COVID-19 hospitalization.
Further research is needed to understand the link between COVID-19, hospitalization, and dry socket incidence.