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Updated: Jan 16, 2026
Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
It Is Time for a New IBS Paradigm
1Department of Hospital Medicine, Osher Center for Integrative Medicine, University of California, San Francisco, CA, USA.
Abstract:
In the 1980s, H. Pylori was discovered as the root cause of peptic ulcer disease and revolutionized treatment. Previously, this illness was treated as a somatoform illness, associated with Type A personalities. Similarly, there is now overwhelming evidence that the root cause of IBS (Irritable Bowel Syndrome) originates from the development of bacterial dysbiosis, yet diagnosis and treatment are not routinely offered to patients. Instead, patients are offered palliative measures. A paradigm shift for IBS management is urgently needed.
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