Related Experiment Video
Updated: Jan 16, 2026
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Redefining Precision: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Comparing
Marcílio de Oliveira Filho1, Miguel Chaves Lenzi2, Pedro Emanuel Carneiro de Lima3
1School of Medicine, Medical College of Barbacena (Faculdade de Medicina de Barbacena), Barbacena, Minas Gerais, Brazil.
Abstract:
Minimally invasive approaches such as laparoscopic surgery (LS) and robotic-assisted surgery (RAS) have transformed colorectal cancer (CRC) management. This systematic review and meta-analysis evaluated nine randomized controlled trials encompassing 2,758 patients to compare RAS and LS regarding perioperative, oncological, and long-term outcomes. RAS showed longer operative time but yielded benefits such as reduced conversion rates, greater lymph node retrieval, and lower circumferential resection margin (CRM) positivity. Both techniques demonstrated comparable safety, mortality, and overall complication rates. While RAS presents certain advantages, further research is required to determine its cost-effectiveness and long-term oncological impact. Trial Registration: PROSPERO CRD420251025102.
