Echocardiographic Markers of Prognosis in Patients Undergoing Ventricular Arrhythmia Ablation
- Lisa Steen Duus 1,2, Maria Dons 1,2, Morten Lock Hansen 1, Rene Worck 1, Martin H Ruwald 1, Arne Johannessen 1, Jim Hansen 1, Tor Biering-Sørensen 1,2,3,4
- Lisa Steen Duus 1,2, Maria Dons 1,2, Morten Lock Hansen 1
- 1Department of Cardiology, Herlev and Gentofte University Hospital, University of Copenhagen, Copenhagen, Denmark.
- 2Center For Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
- 3Department of Cardiology, University Hospital Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
- 4Steno Diabetes Center Copenhagen, Herlev, Denmark.
- 0Department of Cardiology, Herlev and Gentofte University Hospital, University of Copenhagen, Copenhagen, Denmark.
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View abstract on PubMed
Summary
This summary is machine-generated.Echocardiography can identify patients at risk for adverse outcomes after radiofrequency catheter ablation (RFA) for ventricular arrhythmias (VAs). Specific measures predict events like implantable cardioverter-defibrillator (ICD) therapy and mortality, but not VA recurrence.
Area Of Science
- Cardiology
- Electrophysiology
- Medical Imaging
Background
- Radiofrequency catheter ablation (RFA) is increasingly used for ventricular arrhythmias (VAs).
- Identifying patients at risk for adverse outcomes post-RFA is crucial.
Purpose Of The Study
- Evaluate echocardiographic and clinical features in patients undergoing first-time RFA for VAs.
- Identify risk factors for VA recurrence, implantable cardioverter-defibrillator (ICD) therapy, and mortality.
Main Methods
- Retrospective study of 218 patients undergoing first-time RFA for VAs (2011-2022).
- Pre-procedural transthoracic echocardiography analyzed.
- Cox regression models assessed echocardiographic predictors of VA recurrence, appropriate ICD therapy, and mortality.
Main Results
- 41% experienced VA recurrence; 24% had secondary outcomes (ICD therapy/mortality) over 3.1 years median follow-up.
- Ventricular tachycardia patients showed more ventricular dysfunction than premature ventricular contraction patients.
- Echocardiographic measures like LV mass index, LVEF, and GLS predicted secondary outcomes, but not VA recurrence.
Conclusions
- Echocardiographic parameters can identify patients at higher risk of adverse outcomes following RFA for VAs.
- Specific measures predict mortality and ICD therapy, guiding risk stratification.
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