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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
L-Glutamine-Induced Acute Kidney Injury: A Clinical Observation
Soerajja Bhoelan1, Serife Kürül1, Charlotte G Krol1
1Department of Internal Medicine and Nephrology Amphia Hospital, Breda, The Netherlands.
High doses of L-glutamine supplements may cause acute kidney injury (AKI) in elderly patients. This risk is linked to increased ammonia production within the kidneys, highlighting the need for cautious use in those with pre-existing kidney issues.
Area of Science:
- Nephrology
- Biochemistry
- Nutritional Science
Background:
- L-glutamine is the most abundant amino acid in the human body.
- It plays a crucial role in various metabolic processes, including ammonia and bicarbonate generation in the kidneys.
- L-glutamine is widely used as a dietary supplement and generally considered safe.
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