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[Pancreatogenic Diabetes: The Exocrine-Endocrine Axis]
Esteban Pinto K1, Zoltán Berger2
1Unidad de Diabetes, Hospital Dr. Hernán Henríquez Aravena, Temuco, Chile.
None:
Pancreatogenic diabetes is a specific form of diabetes secondary to exocrine pancreatic disease. It is often misclassified or confused with other types of diabetes. It is not a single clinical entity but occurs in association with various exocrine pancreatic disorders, through diffe-rent mechanisms of hyperglycemia. This condition is associated with an increased risk of hypoglycemia, making close clinical monitoring essential.
Aim:
To review the physiological and pathophysiological aspects of the exocrine-endocrine interplay of the pancreas, as well as the clinical features of this specific type of diabetes, in order to support accurate diagnosis, treatment, and follow-up.
Methodology:
Narrative review.
Results:
A multidisciplinary overview of pancreatogenic diabetes is presented, covering its definition, pathogenesis, epidemiology, and management, integrating both endocrine and exocrine pancreatic perspectives.
Conclusions:
The management of pancreatogenic diabetes should be multidisciplinary and individualized, with a focus on preventing and treating malnutrition, and combining insulin therapy with pancreatic enzyme replacement therapy.
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