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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

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Top 10 priorities for future ectopic pregnancy research: an international consensus development study.

Tara Ajith1, Kurt T Barnhart2, Ruth Bender Atik3

  • 1Early Pregnancy and Acute Gynaecology Unit, Women's and Children's Division, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, United Kingdom; Elizabeth Garrett Anderson Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, United Kingdom.

Fertility and Sterility
|September 29, 2025
PubMed
Summary

Future ectopic pregnancy research priorities were identified through international surveys and consensus meetings. These priorities focus on prevention, treatment, and long-term impacts, guiding future research agendas.

Keywords:
Ectopic pregnancyconsensus science methodsmodified Delphi methodreproductive medicineresearch priorities

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Area of Science:

  • Reproductive Health
  • Medical Research Prioritization

Background:

  • Ectopic pregnancy poses significant health risks, necessitating focused research to improve outcomes.
  • Current research gaps hinder effective prevention and treatment strategies for ectopic pregnancy.

Purpose of the Study:

  • To determine and prioritize future research directions for ectopic pregnancy.
  • To establish a consensus-driven agenda for ectopic pregnancy research.

Main Methods:

  • A multi-stage international process involving surveys, systematic reviews, and a consensus development meeting.
  • Utilized the modified nominal group technique with diverse stakeholders, including healthcare professionals and patients.
  • Collated research questions from 855 initial survey participants, clinical guidelines, and Cochrane reviews.

Main Results:

  • Identified 10 key research priorities for ectopic pregnancy from 49 confirmed uncertainties.
  • The consensus involved 37 participants from 10 countries, reflecting global perspectives.
  • Priorities encompass prevention, treatment modalities, and understanding the longer-term consequences of ectopic pregnancy.

Conclusions:

  • The identified priorities address critical clinical needs in ectopic pregnancy care.
  • This research agenda aims to guide funding organizations and researchers toward impactful future studies.
  • The findings will help shape the future research landscape for ectopic pregnancy.