Ginseng Berry Concentrate Alleviates Fatigue in Humans: A Randomized, Placebo-Controlled, Double-Blinded Clinical...

Area of Science:

• Nutritional Science
• Human Physiology
• Pharmacology

Background:

• Ginseng berry concentrate (GBC) is recognized for potential fatigue-reducing properties.
• Limited human studies exist on GBC's efficacy for alleviating fatigue.
• Understanding GBC's impact on daily fatigue is crucial for public health.

Purpose of the Study:

• To investigate the anti-fatigue effects of GBC in adults experiencing daily fatigue.
• To assess changes in fatigue-related metrics following GBC supplementation.
• To evaluate the safety and efficacy of GBC for fatigue management.

Main Methods:

• A randomized, double-blind, placebo-controlled trial was conducted.
• Eighty-eight participants (aged 30-64) with high fatigue scores received GBC (1000 mg) or placebo daily for 8 weeks.
• Fatigue was assessed using Numeric Rating Scale (NRS), Checklist Individual Strength (CIS), and resting lactic acid levels.

Main Results:

• GBC supplementation significantly alleviated fatigue symptoms compared to placebo.
• Improvements were observed in NRS and CIS-physical activity scores.
• Lower resting lactic acid levels were associated with GBC treatment, indicating reduced fatigue.

Conclusions:

• Ginseng berry concentrate (GBC) demonstrates significant efficacy in ameliorating fatigue symptoms in adults.
• The study supports GBC's potential as a natural intervention for managing daily fatigue.
• GBC was found to be safe and effective for individuals experiencing fatigue.