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Microplastics identified in commercial over-the-counter lubricant eyedrops
Julia Jaeger1, Matthew Burke1, Duoduo Wu2
1Eurofins Environment Testing Australia & New Zealand, Dandenong South, VIC, Australia.
Eye (London, England)
|September 30, 2025
Summary
Microplastics were found in all tested commercial eyedrops, posing a significant risk to eye health. This study quantifies microplastic contamination in eye drops, a major source of ocular exposure.
Area of Science:
- Environmental Science
- Ophthalmology
- Materials Science
Background:
- Growing evidence links microplastics to adverse human health effects, particularly on the ocular surface.
- Single-use plastic vials are common for eyedrop packaging and administration.
Purpose of the Study:
- To investigate the presence and quantify microplastic particles in commonly used commercial eyedrops.
- To identify potential sources and implications of microplastic contamination in ophthalmic solutions.
Main Methods:
- Analysis of six commercial tear-replacement solutions (Brands A-F) using light microscopy and Agilent 8700 Laser Direct Infrared (LDIR) chemical imaging.
- Manual counting of microplastic particles and identification of polymer types.
Main Results:
- Microplastics were detected in all analyzed eyedrop brands.
- Particle counts varied widely, from 15 in Brand E to over 18,000 in Brand F.
- Nine distinct microplastic types were identified, including polyethylene, polypropylene, and polystyrene.
Conclusions:
- Commercial eyedrops represent a significant and under-recognized source of ocular microplastic exposure.
- Microplastic contamination may originate from vial degradation or manufacturing processes.
- Patients requiring frequent eyedrop use are particularly vulnerable to chronic ocular exposure.
