The Van Nuys DCIS Prognostic Index →The Silverstein DCIS Prognostic Index
Gary A Ulaner1,2, Sadia Khan3, Nirav B Savalia4
1Molecular Imaging and Therapy, Hoag Family Cancer Institute, Irvine, CA, USA. gary.ulaner@hoag.org.
Annals of Surgical Oncology
|September 30, 2025
Summary
Dr. Melvin J. Silverstein, a pioneer in breast cancer care, is retiring. His legacy includes the Van Nuys DCIS Prognostic Index, crucial for predicting local recurrence after breast-conservation therapy.
Area of Science:
- Oncology
- Surgical Oncology
- Breast Cancer Research
Background:
- Dr. Melvin J. Silverstein, a distinguished figure in breast cancer care, is retiring after a prolific 60-year career.
- He founded the first freestanding breast center in the U.S. and pioneered oncoplastic breast-conservation surgery.
- Dr. Silverstein authored the seminal text on ductal carcinoma in situ (DCIS).


