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Pattern of Respiratory Tract Infections in Nephrotic Syndrome Presented with Relapse
1Dr Ruhul Amin, Assistant Professor, Department of Paediatrics, Sylhet Women's Medical College Hospital, Sylhet, Bangladesh.
Mymensingh Medical Journal : MMJ
|September 30, 2025
Summary
Respiratory tract infections are common in children with relapsing nephrotic syndrome, with pneumonia being the most frequent. Prompt identification and management of these infections are crucial for preventing further relapses and potential chronic kidney disease progression.
Area of Science:
- Pediatrics
- Nephrology
- Infectious Diseases
Background:
- Nephrotic syndrome frequently relapses in children, with infection being a significant trigger.
- Relapses can lead to progressive chronic kidney disease (CKD).
- Understanding the pattern of respiratory tract infections (RTIs) in relapsing nephrotic syndrome is vital for effective management.
Purpose of the Study:
- To investigate the pattern of respiratory tract infections in pediatric nephrotic syndrome patients experiencing relapse.
- To identify common RTIs and their association with nephrotic syndrome relapse.
Main Methods:
- A cross-sectional observational study was conducted on 35 pediatric patients (age 1-12 years) with relapsing nephrotic syndrome.
- Data collected via structured questionnaire and analyzed using SPSS.
- Patients admitted to Dr M R Khan Shishu Hospital & ICH, Bangladesh, from February to August 2020.
Main Results:
- 65.71% of studied children had one or more RTIs.
- Pneumonia was the most common infection (52.17%), followed by bronchiolitis and tonsillitis.
- Common symptoms included swelling, fever, and cough; Streptococcus and COVID-19 were identified pathogens.
Conclusions:
- Respiratory tract infections are a major complication in children with relapsing nephrotic syndrome.
- Pneumonia, bronchiolitis, and tonsillitis showed a higher rate of relapse.
- Findings guide physicians in counseling and treating pediatric nephrotic syndrome patients with infections.
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