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Updated: Jan 16, 2026

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions
Published on: June 24, 2013
Enhancing Microscopic Image Quality With DiffusionFormer and Crow Search Optimization
Subhash Chandra Patel1, Rajesh N Kamath2, T S N Murthy3
1School of Computing Science and Engineering, VIT Bhopal University, Bhopal, India.
Abstract:
Medical Image plays a vital role in diagnosis, but noise in patient scans severely affects the accuracy and quality of images. Denoising methods are important to increase the clarity of these images, particularly in low-resource settings where current diagnostic roles are inaccessible. Pneumonia is a widespread disease that presents significant diagnostic challenges due to the high similarity between its various types and the lack of medical images for emerging variants. This study introduces a novel Diffusion with swin transformer-based Optimized Crow Search algorithm to increase the image's quality and reliability. This technique utilizes four datasets such as brain tumor MRI dataset, chest X-ray image, chest CT-scan image, and BUSI. The preprocessing steps involve conversion to grayscale, resizing, and normalization to improve image quality in medical image (MI) datasets. Gaussian noise is introduced to further enhance image quality. The method incorporates a diffusion process, swin transformer networks, and optimized crow search algorithm to improve the denoising of medical images. The diffusion process reduces noise by iteratively refining images while swin transformer captures complex image features that help differentiate between noise and essential diagnostic information. The crow search optimization algorithm fine-tunes the hyperparameters, which minimizes the fitness function for optimal denoising performance. The method is tested across four datasets, indicating its optimal effectiveness against other techniques. The proposed method achieves a peak signal-to-noise ratio of 38.47 dB, a structural similarity index measure of 98.14%, a mean squared error of 0.55, and a feature similarity index measure of 0.980, which outperforms existing techniques. These outcomes reflect that the proposed approach effectively enhances the quality of images, resulting in precise and dependable diagnoses.
Insights
This study introduces a novel denoising method using a diffusion process, swin transformer, and optimized crow search algorithm to enhance medical image quality. The technique significantly improves diagnostic accuracy, especially for conditions like pneumonia.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Image Processing
Background:
- Medical image noise degrades diagnostic accuracy.
- Effective denoising is crucial, particularly in low-resource settings.
- Pneumonia diagnosis is challenging due to image similarity and data scarcity.
Purpose of the Study:
- To introduce a novel denoising technique for medical images.
- To enhance image quality and reliability for improved diagnoses.
- To address challenges in diagnosing diseases like pneumonia using medical imaging.
Main Methods:
- A novel Diffusion with swin transformer-based Optimized Crow Search algorithm was developed.
- Preprocessing included grayscale conversion, resizing, normalization, and Gaussian noise addition.
- The method integrates diffusion for noise reduction, swin transformer for feature capture, and crow search for hyperparameter optimization.
Main Results:
- The method achieved a Peak Signal-to-Noise Ratio (PSNR) of 38.47 dB.
- Structural Similarity Index Measure (SSIM) reached 98.14%, and Feature Similarity Index Measure (FSIM) was 0.980.
- Mean Squared Error (MSE) was 0.55, outperforming existing denoising techniques across four diverse datasets.
Conclusions:
- The proposed approach effectively enhances medical image quality.
- This leads to more precise and dependable diagnoses.
- The technique shows significant potential for improving diagnostic capabilities in various medical applications.
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