Incidental Detection of Meningioma on ^99mTc-Sestamibi SPECT: A Case Report

A 64-y-old woman presented to our hospital with general weakness, difficulty walking, and a history of kidney stones. Laboratory findings revealed elevated parathyroid hormone and calcium levels. ^99mTc-sestamibi SPECT imaging was performed to evaluate suspected parathyroid adenoma. Although no uptake characteristic of parathyroid adenoma was observed, a focal uptake with delayed washout was unexpectedly detected in the right frontal lobe. Subsequent MRI confirmed the lesion as a meningioma. This case underscores the diagnostic value of ^99mTc-sestamibi scintigraphy in detecting incidental cranial lesions, emphasizing its role in guiding further imaging and clinical management.