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Multimodality CMR diagnosis of double-chambered left ventricle in a child: A case report

Usama Anser1, Lingyi Wen, Lu Zhang

  • 1Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, People's Republic of China.

Medicine
|October 1, 2025
PubMed

Insights

Double-chambered left ventricle (DCLV) can mimic other cardiac conditions, posing diagnostic challenges. Multimodality cardiac magnetic resonance (CMR) imaging is crucial for accurate diagnosis and appropriate management of DCLV.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Congenital Heart Disease

Background:

  • Double-chambered left ventricle (DCLV) is a rare congenital anomaly characterized by a muscular band dividing the left ventricular cavity.
  • DCLV can be misdiagnosed as other conditions like left ventricular noncompaction (LVNC), thrombus, or aneurysm.
  • Multimodality cardiac magnetic resonance (CMR) imaging plays a vital role in diagnosing DCLV.

Purpose of the Study:

  • To highlight the diagnostic utility of CMR in a case of DCLV presenting with ambiguous findings.
  • To emphasize the importance of accurate diagnosis in patients with complex comorbidities.

Main Methods:

  • A case report of a 12-year-old girl with DCLV diagnosed via CMR.
  • CMR findings included a bifid apex with a synchronously contracting muscular band and absence of late gadolinium enhancement.
  • A trabecular-to-compact ratio excluded LVNC, and features were inconsistent with other differential diagnoses.

Main Results:

  • The patient remained asymptomatic with no cardiac complications during a 1-year follow-up.
  • No medical or surgical intervention was required.

Conclusions:

  • DCLV can present with features mimicking serious cardiac conditions, making echocardiography alone insufficient for diagnosis.
  • CMR with tissue characterization is essential for accurate DCLV diagnosis, especially when echocardiography is inconclusive.
  • Early multimodality CMR aids in clarifying morphology and guiding clinical management, preventing misdiagnosis and unnecessary treatments.
Abstract

Keywords:
cardiac magnetic resonancecase reportcongenital heart diseasedouble-chambered left ventriclemultimodality imagingthrombosis

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