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Vaccine Induced Seroreactivity Following Administration of ALVAC-HIV/AIDSVAX®B/E Identified by Common Anti-HIV Test
Siriwat Akapirat1, Elisavet Serti2,3, Punnee Pitisutthithum4
1Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Abstract:
Vaccine-induced seroreactivity (VISR) was evaluated in RV306 and was shown to vary markedly (0-32.5%) among 6 HIV diagnostic tests and 84 algorithms. Our data show that selecting the SD Bioline HIV-1/2 assay and algorithms which exclude the ImmunoComb®II Bispot and Alere™ Determine HIV-1/2 assays would almost eliminate VISR in RV306.
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