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REM Sleep Behavior Disorder

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
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Propofol Exposure Precipitating a Functional Movement Disorder: A Case Report.

Shahbaz Saad¹, Federico Ciardi², Nathan Praschan³

¹Department of Anesthesiology, University of Texas Health Science Center, Houston, Texas, USA, uth.edu.

Case Reports in Anesthesiology

|October 1, 2025

Summary

This summary is machine-generated.

Propofol can trigger functional movement disorders like ataxia and tremors, even in patients without prior neurological issues. Careful anesthetic selection and a biopsychosocial approach are key to managing these rare but distressing reactions.

Keywords:

acute dystonic reaction functional neurological disorder involuntary movements movement disorder parkinsonism

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Area of Science:

Anesthesiology
Neurology
Pharmacology

Background:

Drug-induced movement disorders are rare complications of anesthesia.
Identifying the causative anesthetic agent can be challenging.
Functional movement disorders present unique diagnostic difficulties.

Purpose of the Study:

To report a unique case of functional movement disorder precipitated by propofol.
To highlight the importance of anesthetic agent exclusion in managing such disorders.
To emphasize the utility of a biopsychosocial approach in patient care.

Main Methods:

Case report of a 32-year-old patient experiencing recurrent movement disorders after anesthesia.
Systematic exclusion of anesthetic agents, specifically propofol.
Collaborative management utilizing a biopsychosocial framework across four anesthetic events.

Main Results:

The patient presented with ataxia, dysarthria, chorea, and tremors following multiple anesthetics.
Exclusion of propofol and integrated care planning successfully prevented recurrence of the functional movement disorder.
This case represents the first documented instance of propofol precipitating a functional movement disorder.

Conclusions:

Intraoperative propofol can precipitate functional movement disorders.
A multidisciplinary, biopsychosocial approach is crucial for managing complex anesthetic-related complications.
Careful consideration and exclusion of specific anesthetic agents are vital for preventing iatrogenic neurological symptoms.