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Updated: Jan 16, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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[Hemichorea caused by polycythemia vera]

Nanna Wittrup Sodemann1, Peter Kolind Brask-Thomsen2, Peter Buur van Kooten Niekerk1

  • 1Blodsygdomme, Aarhus Universitetshospital.

Ugeskrift for Laeger
|October 1, 2025
PubMed

Polycythaemia vera (PV) is a chronic myeloproliferative disorder. PV should be suspected with hemoglobin >10.2/9.9 mmol/L (m/f) and/or PV-related features (aquagenic pruritus, erythromelalgia, atypical thrombosis, splenomegaly, thrombocytosis or leukocytosis). This case report highlights the connection between PV and neurological manifestations, including rare symptoms like chorea. An 82-year-old woman presented with sudden choreiform movements, dysarthria, and behavioral changes. Investigations ruled out primary neurological disease and confirmed PV. With treatment, the neurological symptoms resolved.

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