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Updated: Jan 16, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Efficient synthetic approach to m-terphenyl derivatives via arylation of azolium salts
Subarna Kar1, Arya Ramachandran1, Arnab Rit1
1Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, India. arnabrit@iitm.ac.in.
Abstract:
A series of m-terphenyl scaffolds connected to imidazolium salts have been obtained via Ru(II)-catalyzed arylation using haloarenes. The present approach offers structural flexibility, enabling effective access to diverse m-terphenyl based compounds, which may serve as promising candidates for various biological studies, in a single step utilizing readily available starting materials. Mechanistic studies reveal a pathway involving orthometalation, oxidative addition, and reductive elimination followed by a second arylation.
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