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Partial nephrectomy for solid renal masses in polycystic kidneys: open surgical technique.
C O'Connell1, M R Clarkson1, F O'Brien1
1Cork University Hospital, Ireland.
Annals of the Royal College of Surgeons of England
|October 1, 2025
Summary
Open partial nephrectomy is a viable surgical option for kidney cancer in patients with autosomal dominant polycystic kidney disease (ADPKD). This technique preserves kidney function in complex cases, even with multicystic kidneys.
Area of Science:
- Nephrology
- Urologic Oncology
- Surgical Techniques
Background:
- Partial nephrectomy is standard for small renal masses, prioritizing renal function preservation.
- Minimally invasive surgery is common, but open partial nephrectomy remains crucial for complex cases.
- Partial nephrectomy in autosomal dominant polycystic kidney disease (ADPKD) patients presents unique challenges and is infrequently reported.
Purpose of the Study:
- To describe the open surgical technique for partial nephrectomy in patients with multicystic kidneys and solid renal masses.
- To evaluate the feasibility and outcomes of this approach in patients not on renal replacement therapy (RRT).
Main Methods:
- Case series illustrating the open surgical technique for partial nephrectomy.
- Focus on patients with multicystic kidneys and solid renal masses, all with early chronic kidney disease.
- Surgical approach detailed for patients not on RRT.
Main Results:
- Successful open partial nephrectomy was performed in three patients with multicystic kidneys and solid renal masses.
- All patients had early chronic kidney disease, with partial nephrectomy chosen to preserve renal function.
- Patients maintained stable creatinine levels and remained recurrence-free post-surgery.
Conclusions:
- Open partial nephrectomy is an important surgical option for challenging kidney tumors, including those in multicystic kidneys.
- Patients with ADPKD and renal masses should be considered for nephron-sparing surgery.
- Management of ADPKD patients with solid renal masses should align with general population guidelines, favoring kidney-sparing approaches.
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