Related Experiment Video
Updated: Jan 16, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Undescribed isoprenoids obtained from Dictamnus dasycarpus Turcz and their cytotoxic activities
Sun Ye1, Si-Yi Wang2, Yang Xu2
1Key Laboratory of Ningxia Ethnomedicine Modernizaton, Ministry of Education, Ningxia Medical Unlversity, Yinchuan, People's Republic of China.
Abstract:
Four new isoprenoids, dictamtriterpenols B-E (1-4), and fifteen known compounds (5-19) were isolated from Dictamnus dasycarpus Turcz. And the structures of all compounds were determined through techniques such as nuclear magnetic resonance spectroscopy. Compounds 1, 4, 7, 13, and 15 exhibited notable cytotoxic effects against HepG2 cells (IC50 1.55-18.55 μM). Similarly, compounds 1, 3, 8, 9, and 12 demonstrated significant cytotoxicity against A549 cells (IC50 1.63-8.56 μM).

