Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

3.5K
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
3.5K
Adherens Junctions01:24

Adherens Junctions

6.2K
Strong contact points between adjacent cells anchor them to each other, forming tissues. Such anchoring junctions are of two types –  adherens junctions and desmosomes. Adherens junctions are abundant in tissues such as  epithelium and endothelium, forming a continuous zone of adhesion called the adhesion belt. In other tissues, such as  heart muscle, they appear as clusters, linking the cells to produce coordinated heart muscle contraction.
Adherens Junctions are Dynamic
6.2K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

3.5K
Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
3.5K
Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

3.6K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular characterization of superficial zone chondrocytes under pro-inflammatory and biomechanical stress conditions.

PloS one·2026
Same author

AI-assisted preoperative planning improves component sizing accuracy in Oxford unicompartmental knee arthroplasty: a retrospective cohort study with 24-month follow-up.

Journal of orthopaedic surgery and research·2026
Same author

Modified extramedullary femoral referencing is associated with improved femorotibial component alignment consistency and more stable mobile-bearing positional behavior in Oxford medial unicompartmental knee arthroplasty: a retrospective cohort study.

BMC musculoskeletal disorders·2026
Same author

Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence.

Nature communications·2026
Same author

Giant energy exchange rate in mode-coupled resonators enables supercontinuum mechanical frequency combs.

Microsystems & nanoengineering·2026
Same author

A filamentary soft robotic probe for multimodal in utero monitoring of fetal health.

Nature biomedical engineering·2026
Same journal

Taphonomic analysis at Liang Bua reveals the behavioral and technological capabilities of <i>Homo floresiensis</i>.

Science advances·2026
Same journal

Targeting granule initiation and amyloplast structure to create giant starch granules in wheat.

Science advances·2026
Same journal

A meta-analysis of carbon losses and gains from tropical moist forest degradation and regeneration.

Science advances·2026
Same journal

Ancient DNA reveals elite dynastic rule among Iron Age Eurasian Steppe nomads.

Science advances·2026
Same journal

Targeting astrocytic Dp71 attenuates BBB disruption after traumatic brain injury through WTAP-associated m<sup>6</sup>A regulation of MMP2.

Science advances·2026
Same journal

Pancreatic α cells are required for nutrient homeostasis by regulating dynamic β cell networks in islets.

Science advances·2026
See all related articles

Related Experiment Video

Updated: Jan 16, 2026

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion
10:30

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion

Published on: September 4, 2013

10.0K

Dynamic capture enabled by sequential phase-switching adhesion.

Ruozhang Li1, Dongwu Li2, Wenbo Li3

  • 1State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.

Science Advances
|October 1, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a new adhesive strategy using shape memory polymers (SMPs) for dynamic object capture. The SMP-based system efficiently dissipates energy and strengthens upon impact, enabling robust capture in aerospace applications.

More Related Videos

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

8.3K
Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface
13:22

Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface

Published on: November 2, 2011

15.4K

Related Experiment Videos

Last Updated: Jan 16, 2026

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion
10:30

Simultaneously Capturing Real-time Images in Two Emission Channels Using a Dual Camera Emission Splitting System: Applications to Cell Adhesion

Published on: September 4, 2013

10.0K
Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

8.3K
Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface
13:22

Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface

Published on: November 2, 2011

15.4K

Area of Science:

  • Materials Science
  • Aerospace Engineering
  • Robotics

Background:

  • Controllable adhesive interfaces are crucial for dynamic object capture, particularly in aerospace.
  • Existing methods struggle with efficient impact energy dissipation and rapid interface protection during rebound.
  • Complex mechanical and control systems are often required for multi-functional adhesive applications.

Purpose of the Study:

  • To present a novel sequential phase-switching adhesion strategy for full-cycle capture operations.
  • To utilize shape memory polymers (SMPs) for enhanced energy dissipation and interface strengthening.
  • To demonstrate robust dynamic capture, manipulation, and release capabilities.

Main Methods:

  • Engineered an SMP-frame adhesive structure capable of sequential phase-switching.
  • Leveraged the intrinsic viscoelasticity of SMPs for energy dissipation and strengthening.
  • Tested the system's performance in capturing targets with high kinetic energies under free-floating conditions.

Main Results:

  • The SMP-frame adhesive captured targets with normalized kinetic energies exceeding 3800 J/m².
  • The material's viscoelasticity provided strong energy dissipation and rapid interface strengthening.
  • The dynamic strengthening mechanism effectively delayed crack propagation and suppressed rebound.

Conclusions:

  • The sequential phase-switching adhesion strategy offers a paradigm for robust, multifunctional capture in high-dynamics environments.
  • The SMP-based system successfully performed dynamic capture, manipulation, and release.
  • This approach enhances detachment toughness and rebound suppression for aerospace applications.