Related Experiment Video

Updated: Jan 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

33.7K

Feasibility of Low-Volume Atomized Povidone-Iodine as a Peritoneal Antiseptic in Complicated Appendicitis

Kelly R Bates1, Alison J Lehane2, Ashley C Dodd2

  • 1Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

The Journal of Surgical Research
|October 1, 2025
PubMed

Insights

Low-volume atomized povidone-iodine (LVAP) is a new technique for pediatric complicated appendicitis. While not statistically significant, LVAP showed promise in reducing abscesses in contained infections, warranting further investigation.

Area of Science:

  • Pediatric surgery
  • Surgical innovation
  • Infectious disease management

Background:

  • Pediatric complicated appendicitis frequently leads to abscess formation.
  • Current methods like suction, irrigation, or drains lack strong evidence.
  • Novel antiseptic techniques are needed to reduce postoperative complications.

Purpose of the Study:

  • To assess the feasibility of low-volume atomized povidone-iodine (LVAP) for complicated appendicitis.
  • To evaluate LVAP as an antiseptic technique in pediatric cases.
  • To compare LVAP with standard surgical practices.

Main Methods:

  • Retrospective case-control study (2020-2024) at a children's hospital.
  • LVAP involved misted povidone-iodine applied via trocar.
  • Compared LVAP (25 patients) with standard practice (340 patients, 50 matched controls).

Main Results:

  • No adverse events were associated with LVAP.
  • Abscess rates were 16% for LVAP vs. 24% for standard practice (P=0.56).
  • No abscesses occurred with LVAP in contained infections.

Conclusions:

  • LVAP is a feasible new operative technique for pediatric complicated appendicitis.
  • LVAP shows promise in reducing abscess rates for contained infections.
  • Results inform sample size calculations for future powered studies.
Abstract

Keywords:
AppendectomyComplicated appendicitisInfectionLow-volume atomized povidone-iodinePediatricPeritoneal irrigationPostoperative abscess

More Related Videos

Posterior Approach for Debridement of the Psoas Abscess06:02

Posterior Approach for Debridement of the Psoas Abscess

Published on: March 2, 2020

12.0K
Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis04:01

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

2.9K

Related Concept Videos

Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
5.6K
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
510
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
2.2K
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
549
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.2K