Related Experiment Video
Updated: Jan 16, 2026

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
Published on: August 1, 2025
Can cannabinoids alleviate behavioral symptoms in older adults with dementia? A systematic review
Adele Ravelli1, Chiara Ceolin1,2, Mario Virgilio Papa1
1Geriatrics Division, Department of Medicine, University of Padua, Padova, Italy.
Background:
Behavioral and psychological symptoms of dementia (BPSD) affect patients' and caregivers' well-being. Cannabinoids may offer a promising therapeutic option for managing BPSD.
Aims:
This systematic review aims to explore the strengths of using this class of substances in the context of dementia care.
Methods:
We conducted a comprehensive search across Embase Ovid, PubMed, Cochrane Library, APA PsycInfo, and Web of Science, identifying 1839 studies, with 14 selected for full review. Quality was assessed using the Newcastle-Ottawa and the modified Jadad Scales.
Results/Outcomes:
Ten studies (278 participants) were finally included. They showed cannabinoids helped reduce agitation and nocturnal disturbances.
Conclusions/Interpretation:
In conclusion, cannabinoids show promise in managing BPSD in dementia, with good tolerability and safety. Further studies could solidify these findings.
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Pharmacodynamics in Geriatric Patients: Effects of Age
Alzheimer's Disease: Treatment
Drug Dosing: Geriatric Patients
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...

