Related Experiment Video
Updated: Jan 16, 2026

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
Published on: October 20, 2023
Benzodiazepine use in hospitalized older adults: a retrospective observational study
Sandra Torres1, Marta Martins2, Gonçalo Sarmento2
1São João Family Health Unit (São João da Madeira), Unidade Local de Saúde Entre Douro e Vouga, São João da Madeira João da Madeira, Portugal.
Background:
To assess the prevalence and indications for the use of benzodiazepines (BZDs) in patients admitted to an acute geriatric unit and to evaluate changes in their prescriptions.
Methods:
BZD indications were investigated using computerized clinical records. Changes in BZD prescriptions were assessed at the time of discharge.
Results:
Among the 165 patients included (mean age: 86.7 years, 71.5% women), 60 (36.4%) were taking BZD on admission, 58.3% of which were considered inappropriate. At discharge, BZD discontinuation was observed in 11.7% and dose reduction was initiated in 18.3%.
Conclusions:
Most patients using BZD had no clear medical indication. Admission to a geriatric ward resulted in successful discontinuation or dose reduction in a third of patients.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
CNS Depressants: Barbiturates and Benzodiazepines
Drug Dosing: Geriatric Patients
Anxiolytic Drugs: Benzodiazepines and Buspirone
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

