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Related Experiment Video

Updated: Jan 16, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
09:46

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

Published on: March 8, 2015

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Deep brain stimulation for Meige syndrome.

Stephen Jaffee1, Syed Hussain1, Mikayla Spott1

  • 1Department of Neurosurgery, Allegheny Health Network, Pittsburgh, United States.

Surgical Neurology International
|October 2, 2025
PubMed
Summary

Meige syndrome, a cranial dystonia, can be effectively treated with deep brain stimulation (DBS) of the globus pallidus internus (GPi). This case study shows significant symptom improvement in a patient refractory to traditional treatments.

Area of Science:

  • Neurology
  • Neurosurgery

Background:

  • Meige syndrome is a form of cranial dystonia characterized by blepharospasm and oromandibular dystonia.
  • It often co-occurs with conditions like Parkinson's disease and essential tremor.
Keywords:
DystoniaMeigeNeuromodulationStimulation

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  • Current treatments include medications and botulinum toxin, but some patients become refractory.