Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

2.8K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.8K
Pulmonary Function Tests01:25

Pulmonary Function Tests

741
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
741
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.1K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Variability of Monthly Continuous Glucose Monitoring-Derived Metrics With Diabetic Kidney Disease in Type 1 Diabetes.

Diabetes, obesity & metabolism·2026
Same author

Incidence and Prognostic Implications of Mental Disorders Among Patients With a Permanent Pacemaker: A Nationwide Cohort Study.

Journal of the American Heart Association·2026
Same author

The Risks of Mortality, Cardiovascular Events, and Pulmonary Complications in Cancer Patients Who Smoke Cigarettes and Switch to E-Cigarettes: South Korea, 2015‒2022.

American journal of public health·2026
Same author

Stopping Beta-Blockers after Myocardial Infarction. Reply.

The New England journal of medicine·2026
Same author

Clinical Effectiveness and Cost-Effectiveness of Robot-Assisted Versus Conventional Esophagectomy.

Cancer research and treatment·2026
Same author

Non-Selective Beta-Blocker Use Is Associated With Lower Mortality After Decompensation in Cirrhosis: A Nationwide Target Trial Emulation.

Alimentary pharmacology & therapeutics·2026

Related Experiment Video

Updated: Jan 16, 2026

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
03:38

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Published on: June 20, 2025

846

Lobe-Specific Variability in Postoperative Pulmonary Function in Lung Cancer Patients: A Longitudinal Analysis and

Yeong Jeong Jeon1, Sumin Shin2, Sunga Kong3,4

  • 1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Respirology (Carlton, Vic.)
|October 2, 2025
PubMed
Summary

Postoperative lung function after lobectomy for non-small cell lung cancer varies by lobe. Most lobes recover better than predicted, but factors like surgical approach and activity impact long-term outcomes.

Keywords:
lobectomylobe‐specificlung functionnon‐small cell lung cancerrecovery

More Related Videos

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
07:56

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

4.7K

Related Experiment Videos

Last Updated: Jan 16, 2026

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models
03:38

Unilateral Lung Volume Analysis Using Micro-CT for Enhanced Assessment of Pulmonary Fibrosis in Preclinical Models

Published on: June 20, 2025

846
Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
07:56

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

4.7K

Area of Science:

  • Thoracic Surgery
  • Pulmonary Medicine
  • Oncology

Background:

  • Lobectomy is standard for early non-small cell lung cancer (NSCLC).
  • Postoperative pulmonary function decline is a significant clinical challenge.
  • Understanding lobe-specific recovery is crucial for patient management.

Purpose of the Study:

  • To investigate pulmonary function changes after lobectomy for NSCLC.
  • To compare observed lung function with predicted postoperative (PPO) values.
  • To analyze lobe-specific variability in pulmonary function recovery.

Main Methods:

  • Prospective cohort study of 419 NSCLC patients undergoing lobectomy.
  • Pulmonary function tests (FVC, FEV1, DLCO) pre- and post-surgery (1-12 months).
  • Comparison of observed vs. traditional segmental PPO values; mixed-effects models for lobe-specific analysis.

Main Results:

  • Left upper and right lower lobes showed early recovery (similar to PPO by 2 weeks).
  • Other lobes had ~25% reduction in FVC, FEV1, DLCO.
  • Observed function exceeded PPO values for all lobes by 3 months.
  • Surgical approach and reduced physical activity impacted 6-month recovery.

Conclusions:

  • Postoperative pulmonary function recovery after lobectomy is lobe-dependent.
  • Most lobes demonstrate better-than-predicted recovery.
  • Accurate prediction requires considering lobe-specific factors and compensatory mechanisms.