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The Emory Treatment Resistance Interview for PTSD-Short Version (E-TRIP-S).

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Summary
This summary is machine-generated.

A simplified scale, the Emory Treatment Resistance Interview for PTSD-Short version (E-TRIP-S), helps identify posttraumatic stress disorder (PTSD) treatment resistance. Many patients show limited benefit from prior therapies, but the E-TRIP-S may guide future treatment selection.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Medical Informatics

Background:

  • Treatment resistance is common in posttraumatic stress disorder (PTSD).
  • The Emory Treatment Resistance Interview for PTSD (E-TRIP) was previously developed to assess treatment resistance.
  • A simplified version, the E-TRIP-Short (E-TRIP-S), was created to evaluate responses to first-line PTSD treatments.

Purpose of the Study:

  • To introduce and validate the E-TRIP-Short (E-TRIP-S) as a simplified measure of treatment resistance in PTSD.
  • To assess the preliminary utility of the E-TRIP-S in a US military population undergoing evaluation for PTSD treatment.

Main Methods:

  • 102 US military personnel and veterans evaluated for PTSD were interviewed by trained assessors.
  • The E-TRIP-S was administered to assess prior responses to evidence-based psychotherapies and medications.
  • Descriptive statistics were used to analyze E-TRIP-S scores and evaluate the measure's utility.

Main Results:

  • The majority of patients seeking intensive outpatient PTSD care showed elevated E-TRIP-S scores, indicating treatment resistance.
  • Low percentages of patients reported significant benefit from prior psychotherapy (28.2%) or medication (23.2%) for PTSD symptoms.
  • Approximately 25% of patients who did not benefit from one treatment modality reported significant benefit from the alternative modality.

Conclusions:

  • The E-TRIP-S provides a simplified method for assessing treatment resistance in PTSD patients.
  • Preliminary findings suggest the E-TRIP-S can inform clinical treatment selection and aid research by identifying treatment-resistant individuals for clinical trials.